Purvee singh biography of michael
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Informatics Publishing Limited
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Singh, S. K.
- Status and Scope of Medicinal Plants in Bhagirathi Valley of Garhwal, Uttaranchal-conservation Strategy
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Indian Forester, Vol 129, No 8 (2003), Pagination: 950-963Abstract
Conservation of medicinal/aromatic plants and the environment will be possible only with the precondition that our political leadership and policy makers become alive to this problem and take some really strong decisions. Since the Forest Department has to play a major role in this initiative by virtue of being the dominant custodian of the patural resource of land and forest, it should be ready for a major attitudinal change in favour of an ecosystems approach to forestry. The public of Uttaranchal are the predominant stakeholders, and will have to assert themselves against the threat of grazing, pilferage and fire. Our scientists•
Dr. Wayne A. I. Frederick was appointed the seventeenth president of Howard University in 2014. He previously served as Provost and Chief Academic Officer. Most recently, the Howard University Board of Trustees selected Dr. Frederick to serve as the distinguished Charles R. Drew Professor of Surgery.
A distinguished scholar and administrator, Dr. Frederick has advanced Howard University's commitment to student opportunity, academic innovation, public service, and fiscal stability. Early in his tenure as president, Dr. Frederick pursued initiatives to streamline and strengthen university operations. He has overseen a series of reform efforts, including the expansion of academic offerings, establishing innovative programs to support student success and the modernization of university facilities.
As an undergraduate, Dr. Frederick was admitted to Howard University's B.S./M.D. dual degree program. He completed the requirements for both degrees in six years, allowing him to earn his Ba
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Dario Alessi's Research Group
Motivated by the lack of a molecular understanding and a treatment that slows down the progression of Parkinson’s disease, our research focuses on the leucine-rich repeat kinase-2 (LRRK2) pathway, as mutations that increase the kinase activity of LRRK2, represent one of the most common inherited causes of Parkinson’s disease. The goal of our work is to undertake high quality rigorous research to develop a robust framework of knowledge of how the LRRK2 signalling pathways is regulated, to develop improved methods to better diagnose and treat Parkinson’s disease.
LRRK2 is a large multidomain protein consisting of two catalytic domains namely an atypical GTPase and a protein kinase domain. Pathogenic mutations that activate LRRK2 are found in the kinase and GTPase as well as other domains and are thought to destabilise the inactive conformation of LRRK2 1. We have found that LRRK2 phosphorylates a subgroup of Rab GTPase proteins (Rab1, Rab3, Rab8, R