Jarrett lemaster biography definition
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Abstract
Radical S-adenosyl-l-methionine (SAM) enzymes leverage the properties of one or more iron- and sulfide-containing metallocenters to catalyze complex and radical-mediated transformations. By far the most populous superfamily of radical SAM enzymes are those that, in addition to a 4Fe–4S cluster that binds and activates the SAM cofactor, also bind one or more additional auxiliary clusters (ACs) of largely unknown catalytic significance. In this report we examine the role of ACs in two RS enzymes, PapB and Tte1186, that catalyze formation of thioether cross-links in ribosomally synthesized and post-translationally modified peptides (RiPPs). Both enzymes catalyze a sulfur-to-carbon cross-link in a reaction that entails H atom transfer from an unactivated C–H to initiate catalysis, followed by formation of a C–S bond to yield the thioether. We show that both enzymes tolerate substitution of SeCys instead of Cys at the cross-linking site, allowing the systems to be subjected
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Nefarious (film)
2023 Christian horror-thriller film
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| Based on | A Nefarious Plot by Steve Deace |
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| Cinematography | Jason Head |
| Edited by | Brian Jeremiah Smith |
| Music by | Bryan E. Miller |
Production | Believe Entertainment |
| Distributed by | Soli Deo Gloria Releasing |
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Running time | 97 minutes |
| Country | United States |
| Language | English |
| Budget | $1 million[1] |
| Box office | $5.8 million[2] |
Nefarious is a 2023 American independentChristianhorror-thriller film written and directed by Cary Solomon and Chuck Konzelman, based on Steve Deace's 2016 novel A Nefarious Plot. It stars Jordan Belfi as a psychiatrist who must determin
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Homestead (film)
2024 American film
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| Directed by | Ben Smallbone |
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| Based on | Black Autumn by Jeff Kirkham and Jason Ross |
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| Starring | |
| Cinematography | Matthew Rivera |
| Edited by | John Puckett |
| Music by | Benjamin Backus |
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| Distributed by | Angel Studios |
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Running time | 110 minutes |
| Country | United States |
| Language | English |
| Box office | $20.8 million[1] |
Homestead is a 2024 American post-apocalypticdrama bio directed bygd Ben Smallbone and written by Phillip Abraham, Leah Bateman and Jason Ross. Its stars Neal McDonough, Dawn Olivieri, Currie Graham, Susan Misner, Bailey jaga, Jesse Hutch, Kevin Lawson, Kearran Giovanni, Tyler Lofton, E